Bioactivity | Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (Compound dP) exhibits mutagenicity for Escherichia coli and Salmonella typhimurium, that induces the conversion between GC and AT through replication error. eoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one is stable in Escherichia coli, and can be detected at wavelength >300 nM[1]. |
CAS | 126128-42-5 |
Formula | C11H15N3O5 |
Molar Mass | 269.25 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Negishi K, et al., The mechanism of mutation induction by a hydrogen bond ambivalent, bicyclic N4-oxy-2'-deoxycytidine in Escherichia coli. Nucleic Acids Res. 1997 Apr 15;25(8):1548-52. |